MAIL
The outbound port settings apply to all outbound SMTP sessions. If you change an outbound port number to a nonstandard value, the server cannot establish SMTP connections with servers that listen for SMTP requests on the standard port. Similarly, if you set up the server to send SMTP over SSL only, disabling the outbound SMTP TCP/IP port, the server cannot establish SMTP connections with a remote server that accepts SMTP connections over the TCP/IP port only.
To change outbound SMTP port settings
1. From the Domino Administrator, click the Configuration tab and then open the Server document for the server that runs the SMTP service.
2. Click the Ports - Internet Ports - Mail tab.
3. In the Mail (SMTP Outbound) column, complete these fields, and then click Save & Close: